Hanibuchi Masaki, Yano Seiji, Edakuni Nobutaka, Inayama Mami, Sone Saburo
Department of Internal Medicine and Molecular Therapeutics, Course of Bioregulation and Medical Oncology, The University of Tokushima School of Medicine, Tokushima, Japan.
J Med Invest. 2004 Aug;51(3-4):234-7. doi: 10.2152/jmi.51.234.
A 71-year-old man was referred to our hospital for further examination of abnormal sputum cytology. No abnormal nodular shadows were detected in chest X-ray and chest CT. The location of the tumor was clearly identified as a defect of autofluorescence by autofluorescence bronchoscopy at the bifurcation between the left B1+2 and B3 bronchi, whereas it was quite difficult by conventional bronchoscopy. Transbronchial biopsy revealed squamous cell carcinoma. Further examinations yielded the diagnosis of early-stage lung cancer. Photodynamic therapy was performed and complete response was confirmed. This case indicates the efficacy of autofluorescence bronchoscopy for detecting early-stage lung cancer.
一名71岁男性因痰液细胞学异常被转诊至我院进一步检查。胸部X线和胸部CT未发现异常结节影。通过自发荧光支气管镜检查,肿瘤位置在左B1+2和B3支气管分叉处被明确识别为自发荧光缺损,而传统支气管镜检查很难做到这一点。经支气管活检显示为鳞状细胞癌。进一步检查确诊为早期肺癌。进行了光动力治疗并确认完全缓解。该病例表明自发荧光支气管镜检查在检测早期肺癌方面的有效性。