Norhayati M M, Mazlyzam A L, Asmah R, Fuzina H, Aminuddin B S, Ruszymah B H I, Fauziah O
Institute of Bioscience, Universiti Putra Malaysia.
Med J Malaysia. 2004 May;59 Suppl B:184-5.
Scanning Electron Microscopy (SEM) and Transmission Electron Microscopy (TEM) evaluation were carried out in the in vivo skin construct using fibrin as biomaterial. To investigate its progressive remodeling, nude mice were grafted and the Extracellular Matrix (ECM) components were studied at four and eight weeks post-grafting. It was discovered that by 4 weeks of remodeling the skin construct acquired its native structure.
使用纤维蛋白作为生物材料,对体内皮肤构建体进行了扫描电子显微镜(SEM)和透射电子显微镜(TEM)评估。为了研究其渐进性重塑,将裸鼠进行移植,并在移植后四周和八周研究细胞外基质(ECM)成分。结果发现,经过4周的重塑,皮肤构建体获得了其天然结构。