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[对一组工人进行28年随访的死亡模式:曼雷萨研究]

[Patterns of mortality in a cohort of workers followed during 28 years: the Manresa study].

作者信息

Puig Teresa, Varas Cristina, Pérez Iñaki, Abadal Lluís Tomàs, Balaguer Vintró Ignasi

机构信息

Servicio de Epidemiología Clínica, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

出版信息

Rev Esp Cardiol. 2004 Oct;57(10):924-30.

Abstract

INTRODUCTION AND OBJECTIVES

To describe mortality patterns in a cohort of workers followed for 28 years, to estimate possible trends, and to compare the findings with those for the general population.

SUBJECTS AND METHOD

The cohort included 1059 healthy male workers aged 30 to 59 years and followed for 28 years. Physical examinations and structured interviews were carried out every 5 years. Deaths were recorded from death certificates. The standardized mortality ratio (SMR) was calculated using sex- and age-specific mortality rates for the Catalan population as a reference for the same time period.

RESULTS

The number of observed deaths in this cohort was 259 (24%). The main causes of death were cardiovascular diseases (n = 90, 35%) and cancer (n = 90, 35%). No excess mortality was observed in the cohort in comparison to the general population. All-cause mortality was lower, and cause-specific mortality was lower than or similar to rates in the general population. Overall, 382 deaths were expected, resulting in a significantly lower standardized mortality ratio of 67.7% (95% CI: 59.7%-76.5%).

CONCLUSIONS

The patterns of mortality in this cohort of male workers were similar to those in the general population. Total mortality was lower than expected--evidence of the "healthy worker effect" which was particularly strong during the early part of the follow-up period.

摘要

引言与目的

描述一组随访28年的工人的死亡模式,估计可能的趋势,并将结果与普通人群的结果进行比较。

对象与方法

该队列包括1059名年龄在30至59岁之间的健康男性工人,随访28年。每5年进行一次体格检查和结构化访谈。根据死亡证明记录死亡情况。以加泰罗尼亚人群同期的性别和年龄特异性死亡率为参考,计算标准化死亡比(SMR)。

结果

该队列中观察到的死亡人数为259人(24%)。主要死因是心血管疾病(n = 90,35%)和癌症(n = 90,35%)。与普通人群相比,该队列未观察到超额死亡率。全因死亡率较低,特定病因死亡率低于或与普通人群相似。总体而言,预期死亡382人,标准化死亡比显著降低至67.7%(95%CI:59.7%-76.5%)。

结论

该组男性工人的死亡模式与普通人群相似。总死亡率低于预期——这是“健康工人效应”的证据,在随访期早期尤为明显。

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