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[两例病因罕见的小肠缺血病例]

[Two cases of small bowel ischemia due to unusual cause].

作者信息

Amendolara M, Carpentieri L, Balbi T, D' Elia A, Perri S, Baldon S, Farruggio A, Biasiato R

机构信息

Unità Operativa Semplice, Chirurgia Videoassistita, ASL 17 -- Regione Veneto, Monselice (PD).

出版信息

Minerva Chir. 2004 Oct;59(5):517-22.

Abstract

The authors report 2 cases of small bowel ischemia due to unusual cause. In both cases, vasculopathy was the cause of ischemia, but with a different etiology. In the first case, a mesenteric inflammatory veno-occlusive disease, with striking features of extensive phlebitis and venulitis affecting the veins of the small intestine and mesentery, without arterial involvement of this district was observed and histological examination showed inflammatory lymphocytic infiltrates and myointimal hyperplasia of the veins. The second case affected by intestinal ischemia from secondary and multiple cholesterol embolism, the histological examination showed inflammatory infiltrates with (lymphocytes and granulocytes) in the vessels of submucosal mesenteric area, by loose intimal fibrosis incorporating cholesterol clefts. Both patients required surgical exploration with resection of ischemic bowel. In the second case laparoscopy was the initial approach which allowed to identify the extension of ischemia with special regard to the perforation. The ultimate diagnosis is possible only with histological examination. Clinically, patients show the general signs of intestinal ischemia with pain, vomiting and bloody diarrhea. Prognosis depends on the extension of the lesions and the early surgical treatment.

摘要

作者报告了2例由不寻常原因引起的小肠缺血病例。在这两个病例中,血管病变是缺血的原因,但病因不同。在第一个病例中,观察到一种肠系膜炎性静脉闭塞性疾病,其显著特征是广泛的静脉炎和小静脉炎影响小肠和肠系膜的静脉,该区域无动脉受累,组织学检查显示静脉有炎性淋巴细胞浸润和肌内膜增生。第二个病例是由继发性和多发性胆固醇栓塞引起的肠道缺血,组织学检查显示在肠系膜黏膜下区域的血管中有炎性浸润(淋巴细胞和粒细胞),伴有包含胆固醇裂隙的疏松内膜纤维化。两名患者均需要进行手术探查并切除缺血肠段。在第二个病例中,腹腔镜检查是初始方法,它能够确定缺血的范围,特别是关于穿孔的情况。只有通过组织学检查才能做出最终诊断。临床上,患者表现出肠道缺血的一般体征,如疼痛、呕吐和血性腹泻。预后取决于病变的范围和早期手术治疗。

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