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原发性淀粉样变性的一种不寻常表现。

An unusual presentation of primary amyloidosis.

作者信息

Dursun Mehmet, Ayyildiz Orhan, Yilmaz Serif, Bilici Aslan

机构信息

Department of Gastroenterology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.

出版信息

Saudi Med J. 2004 Oct;25(10):1478-81.

Abstract

A 65-year-old male patient presented with right upper-quadrant abdominal pain. Ultrasonography revealed hypoechoic lesion in the perihepatic and intraparenchymal area. Computed tomography (CT) showed hypodense lesion in the same localization. A fine needle biopsy specimen of the perihepatic lesion was hemorrhagic. On abdominal CT, the liver showed enhancement, but the spleen did not enhance. The spleen could not be detected by scintigraphic imaging using Tc99m sulfur dioxide. A diagnosis of primary amyloidosis was made by renal biopsy. Melphalan 10 mg/day for 4 days/month was started. The clinical and radiological follow up demonstrated a resorption of the hematoma. The patient is still alive at the eighth month of therapy.

摘要

一名65岁男性患者出现右上腹腹痛。超声检查显示肝周和肝实质内区域有低回声病变。计算机断层扫描(CT)显示同一部位有低密度病变。肝周病变的细针穿刺活检标本有出血。腹部CT检查时,肝脏有强化,但脾脏未强化。使用锝99m二氧化硫进行的闪烁成像未检测到脾脏。通过肾活检确诊为原发性淀粉样变性。开始使用美法仑,10毫克/天,每月服用4天。临床和影像学随访显示血肿吸收。患者在治疗的第八个月仍然存活。

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