Sherman Paul M, Yousem David M, Loevner Laurie A
Russell H. Morgan Department of Radiology and Radiological Sciences, Division of Neuroradiology, Johns Hopkins Medical Institution, Baltimore, MD, USA.
AJNR Am J Neuroradiol. 2004 Oct;25(9):1603-7.
The growth of cross-sectional imaging has increased the detection of nonpalpable head and neck masses. We sought to determine the reliability of CT-guided fine-needle aspiration (FNA) over 216 consecutive cases.
We retrospectively reviewed histopathologic findings and notes from 216 consecutive head and neck CT-guided FNA procedures performed between 1993 and 2003. Types of needles used, passes required, lesion location, initial cytologic diagnosis, and final histopathologic or clinical diagnosis were reviewed.
Diagnostic samples were obtained in 195 (90.3%) of the lesions, with 21 (9.7%) inadequate samples. A correct diagnosis was made in 191 cases (88.4%). Final FNA diagnosis was discordant in four (1.9%) specimens, with the parapharyngeal space and parotid gland having the highest rate of inaccuracy. The range in number of passes required for final diagnosis was one to six (mode, 2.0 passes per specimen; median, 2.0; mean, 2.6; standard deviation, 1.13). In 135 (63%) of 216 cases, definitive surgical pathologic results, including findings for the four discordant specimens, were obtained. Of the nondiagnostic specimens, six (29%) of 21 went to surgery, five (83%) of six were neoplastic, and one (17%) of six was fibrous tissue. The remainder underwent clinical and imaging follow-up.
CT-guided FNA is a safe, well tolerated, and accurate for the diagnosis of head and neck lesions. In our series, the percentage of diagnostic samples obtained improved compared with prior reports. The low diagnostic error rate overall was possibly related to onsite evaluation by the cytopathologist and to improved FNA technique.
横断面成像技术的发展增加了对头颈部不可触及肿块的检出率。我们试图确定连续216例病例中CT引导下细针穿刺抽吸(FNA)的可靠性。
我们回顾性分析了1993年至2003年间连续进行的216例头颈部CT引导下FNA手术的组织病理学结果和记录。对所用针的类型、所需穿刺次数、病变位置、初始细胞学诊断以及最终组织病理学或临床诊断进行了回顾。
195例(90.3%)病变获得了诊断性样本,21例(9.7%)样本不足。191例(88.4%)做出了正确诊断。4例(1.9%)标本的最终FNA诊断不一致,咽旁间隙和腮腺的诊断错误率最高。最终诊断所需穿刺次数范围为1至6次(众数,每个标本2.0次穿刺;中位数,2.0;平均数,2.6;标准差,1.13)。216例中的135例(63%)获得了明确的手术病理结果,包括4例诊断不一致标本的结果。在未诊断出的标本中,21例中有6例(29%)进行了手术,6例中有5例(83%)为肿瘤性病变,6例中有1例(17%)为纤维组织。其余病例进行了临床和影像学随访。
CT引导下FNA对诊断头颈部病变是安全、耐受性良好且准确的。在我们的系列研究中,获得诊断性样本的百分比与先前报告相比有所提高。总体较低的诊断错误率可能与细胞病理学家的现场评估以及FNA技术的改进有关。