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手部掌骨和指骨结核

Tuberculosis of the metacarpals and phalanges of the hand.

作者信息

Subasi Mehmet, Bukte Yasar, Kapukaya Ahmet, Gurkan Fuat

机构信息

Department of Orthopaedic Surgery, University of Dicle, Diyarbakir, Turkey.

出版信息

Ann Plast Surg. 2004 Nov;53(5):469-72. doi: 10.1097/01.sap.0000130708.80606.6a.

Abstract

Skeletal tuberculosis (TB) is less common than the pulmonary form. Involvements of the metacarpals and phalanges of the hand are infrequent. The authors report their experience with treatment and outcome of TB of the metacarpals and phalanges of the hand in 7 patients. There were 4 women and 3 men in the study who ranged in age from 3 to 60 years (average age, 22.7 years). The duration of complaints at presentation ranged from 4 to 17 months (average, 9 months). The most common presentation was pain and swelling. The presumptive preoperative diagnoses were bone tumor in 4 patients, spina ventosa in 2, and chronic pyogenic osteomyelitis in 1 patients. The results of the laboratory examination showed a mild increase in the erythrocyte sedimentation rate. No patient had an active tubercular lesion or history of pulmonary disease. The diagnosis was based on the clinical picture and radiographic features, and was confirmed by open biopsy. No patient had bony debridement or arthrodesis to control the infection. The treatment of all patients began with a 4-drug regimen for 2 months, followed by a 2-drug regimen for 10 months. The mean follow-up was 30.28 months (range, 16-52 months). At the time of the last follow-up, all lesions had healed with no recurrence. The functional results were satisfactory in all patients. One patient with thumb metacarpophalangeal TB had joint irregularity and thumb metacarpal shortening. Arthrodesis was not needed in any patient. TB of the metacarpals and phalanges of the hand can be difficult to diagnose during the early stages. TB should be suspected in cases of long-standing pain and swelling in the metacarpals and phalanges. It is necessary to keep TB in mind when making the differential diagnosis of several osseous pathologies.

摘要

骨结核比肺结核少见。手部掌骨和指骨受累的情况并不常见。作者报告了他们对7例手部掌骨和指骨结核的治疗经验及结果。研究中有4名女性和3名男性,年龄在3至60岁之间(平均年龄22.7岁)。就诊时主诉的持续时间为4至17个月(平均9个月)。最常见的表现是疼痛和肿胀。术前初步诊断为骨肿瘤4例,骨气臌2例,慢性化脓性骨髓炎1例。实验室检查结果显示红细胞沉降率轻度升高。所有患者均无活动性结核病灶或肺部疾病史。诊断基于临床表现和影像学特征,并经开放活检证实。所有患者均未进行骨清创或关节融合术来控制感染。所有患者的治疗均先采用4种药物联合治疗2个月,然后采用2种药物联合治疗10个月。平均随访时间为30.28个月(范围16 - 52个月)。在最后一次随访时,所有病灶均已愈合,无复发。所有患者的功能结果均令人满意。1例拇指掌指关节结核患者出现关节畸形和拇指掌骨缩短。所有患者均无需进行关节融合术。手部掌骨和指骨结核在早期可能难以诊断。对于掌骨和指骨长期疼痛和肿胀的病例,应怀疑骨结核。在对几种骨病进行鉴别诊断时,有必要考虑到骨结核。

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