Kucharzewski Marek, Sułkowski Leszek, Sieroń Aleksander
Oddział Kliniczny Chirurgii Ogólnej SI. AM w Bytomiu.
Pol Merkur Lekarski. 2004 Jun;16(96):595-6.
Heat-shock proteins (HSP) are a group of proteins, whose production in induced as a intracellular response to different kinds of stresses. They are also included in the group of chaperones, which are involved in protein folding and repairing of denatured proteins in the cells. Because of the protective role of HSP on the cellular level, many studies are focused on the role of heat shock proteins in anti-carcinogenic effect. The present study is a review of the literature regarding the value of HSP in the carcinogenic process.
热休克蛋白(HSP)是一组蛋白质,其产生是作为细胞对各种应激的细胞内反应而被诱导的。它们也包含在伴侣蛋白组中,伴侣蛋白参与细胞内蛋白质的折叠和变性蛋白质的修复。由于热休克蛋白在细胞水平上的保护作用,许多研究聚焦于热休克蛋白在抗癌作用中的角色。本研究是关于热休克蛋白在致癌过程中价值的文献综述。