Aksoy A, Schulz D, Yilmaz A, Canbeyli R
Psychobiology Laboratory, Department of Psychology, Bogazici University, Istanbul, Turkey.
Int J Neurosci. 2004 Dec;114(12):1513-20. doi: 10.1080/00207450490509131.
Separate groups of female Wistar rats were tested every three months over a year to assess the extent of seasonal variability in the behavioral despair model of depression consisting of 2 swim tests separated by 24 h. There was a significant seasonal variability in the duration of immobility in the swim tests; duration of immobility was shorter in August and November than in February and May. These findings suggest reduced immobility and susceptibility to behavioral despair in summer and fall compared to winter and spring.
在一年的时间里，每隔三个月对不同组的雌性Wistar大鼠进行测试，以评估由两次间隔24小时的游泳测试组成的抑郁症行为绝望模型中的季节性变化程度。游泳测试中的不动时间存在显著的季节性变化；八月和十一月的不动时间比二月和五月短。这些发现表明，与冬季和春季相比，夏季和秋季的不动时间减少，对行为绝望的易感性降低。
