Shiraishi Kazuhiro, Higuchi Yoshihisa, Ozawa Kyoko
Department of Pediatrics, Utano National Hospital, Kyoto, Japan.
Brain Dev. 2004 Dec;26(8):539-41. doi: 10.1016/j.braindev.2004.02.014.
We report a patient who developed relapsing-remitting multiple sclerosis (MS) at 8 years old, and then had a progressive clinical course and dystonia. Dystonia of the patient is probably due to a lesion of the basal ganglia. Abnormal posture or movement disorder is very rarely found in MS, and progressive clinical course is also rare in childhood. The patient is worthy of attention because of his childhood onset, progressive clinical course and dystonia.
我们报告了一名8岁时患复发缓解型多发性硬化症(MS)的患者,随后其病情呈进行性发展并出现了肌张力障碍。该患者的肌张力障碍可能是由于基底神经节病变所致。在MS中很少发现异常姿势或运动障碍,而且在儿童期出现病情进行性发展的情况也很罕见。鉴于该患者发病于儿童期、病情呈进行性发展且伴有肌张力障碍,值得关注。