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类风湿关节炎:颈椎的评估与外科治疗

Rheumatoid arthritis: evaluation and surgical management of the cervical spine.

作者信息

Shen Francis H, Samartzis Dino, Jenis Louis G, An Howard S

机构信息

Department of Orthopedic Surgery, Rush Medical College, Rush-Presbyterian-St. Luke's Medical Center, 1725 West Harrison Street, Suite 1063 POB, Chicago, IL 60612, USA.

出版信息

Spine J. 2004 Nov-Dec;4(6):689-700. doi: 10.1016/j.spinee.2004.05.001.

Abstract

BACKGROUND CONTEXT

Rheumatoid arthritis is a debilitating polyarthropathic degenerative condition. Eighty-six percent of patients with rheumatoid arthritis have cervical spine involvement. Often these lesions are clinically asymptomatic or symptoms are erroneously attributed to peripheral manifestation of the patient's rheumatoid disease. Because these lesions are common and missed diagnosis can result in death, early recognition is vital.

PURPOSE

The purpose of this literature review is to identify common lesions present in the rheumatoid neck and review diagnostic methods as well as treatment options for those requiring surgical intervention.

STUDY DESIGN

A review of the English medical literature with focus on more recent studies on the presentation, diagnosis, management, surgical treatment and clinical outcomes of rheumatoid arthritis of the cervical spine.

METHODS

A comprehensive literature review of the English medical literature obtained through Medline up to November 2003 was performed identifying relevant and more recent articles that addressed the presentation, evaluation, surgical management and outcomes of rheumatoid patients with cervical spine involvement.

RESULTS

If left untreated, a large percentage of rheumatoid patients with cervical spine involvement progress toward complex instability patterns resulting in significant morbidity and mortality. Once myelopathy occurs, prognosis for neurologic recovery and long-term survival is poor. In properly selected patients, anterior and/or posterior cervical procedures can prevent neurologic injuries and preserve remaining function.

CONCLUSION

Cervical spine involvement in the rheumatoid patient is common and progressive. Early diagnosis and treatment is imperative; however, surgical intervention should be considered carefully because associated morbidity and mortality is high.

摘要

背景

类风湿性关节炎是一种使人衰弱的多关节退行性疾病。86%的类风湿性关节炎患者有颈椎受累情况。这些病变通常在临床上无症状,或者症状被错误地归因于患者类风湿疾病的外周表现。由于这些病变很常见,漏诊可能导致死亡,所以早期识别至关重要。

目的

本综述的目的是确定类风湿性颈椎常见的病变,并回顾诊断方法以及对需要手术干预患者的治疗选择。

研究设计

对英文医学文献进行综述,重点关注关于颈椎类风湿性关节炎的表现、诊断、管理、手术治疗及临床结果的最新研究。

方法

对通过Medline检索到的截至2003年11月的英文医学文献进行全面综述,确定涉及颈椎受累类风湿患者的表现、评估、手术管理及结果的相关且最新的文章。

结果

如果不进行治疗,很大一部分颈椎受累的类风湿患者会发展为复杂的不稳定模式,导致严重的发病率和死亡率。一旦发生脊髓病,神经恢复和长期生存的预后很差。在适当选择的患者中,颈椎前路和/或后路手术可以预防神经损伤并保留剩余功能。

结论

类风湿患者颈椎受累很常见且呈进行性。早期诊断和治疗势在必行;然而,由于相关的发病率和死亡率很高,应谨慎考虑手术干预。

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