Successful desensitization to enfuvirtide after a hypersensitivity reaction in an HIV-1-infected man.
作者信息
DeSimone Joseph A, Ojha Ambrish, Pathak Rolee, Cohn John
机构信息
Division of Infectious Diseases, Thomas Jefferson University, Philadelphia, PA 19107, USA.
出版信息
Clin Infect Dis. 2004 Nov 15;39(10):e110-2. doi: 10.1086/425502. Epub 2004 Oct 26.
DOI:10.1086/425502
PMID:15546072
Abstract
We report a case of successful, rapid desensitization to enfuvirtide after a hypersensitivity reaction in a man with highly drug-resistant human immunodeficiency virus type 1 infection. The patient was desensitized in a monitored intensive care unit and tolerated the rapid desensitization protocol without any serious adverse effects. This case illustrates the ability to safely desensitize patients with limited treatment options who require enfuvirtide therapy.
摘要
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