Jordanova V, Wickramesinghe C, Gerada C, Prince M
Institute of Psychiatry, De Crespigny Park, London SE5 8AF, UK.
Psychol Med. 2004 Aug;34(6):1013-24. doi: 10.1017/s0033291703001727.
The most widely used survey measures in psychiatry, the Composite International Diagnostic Interview (CIDI) and the Clinical Interview Schedule-Revised (CIS-R) have generated estimates of psychiatric morbidity that show considerable variation. Doubts have been raised regarding the validity of these structured lay interviewer assessments. There have been no direct comparisons of the performances of these instruments against a common, established criterion.
A total of 105 unselected primary care attendees were each interviewed with CIDI, CIS-R and SCAN in a single sitting with random order of administration. SCAN was administered by a SCAN trained psychiatrist, and CIDI and CIS-R by a public health doctor. Concordance was estimated for all ICD-10 neurotic disorders. We assessed the overall discriminability of the CIS-R morbidity scale using a receiver operating characteristic (ROC) analysis.
The concordance for CIDI for ICD-10 diagnoses was moderate to excellent (kappa= 0.58-0.97). Concordance for CIS-R ranged between poor and moderate (kappa = 0.10-0.65). The area under the ROC curve for the CIS-R morbidity scale with respect to any ICD-10 disorder [0.87 (95% CI 0.79-0-95)] indicated good overall discriminability, but poor sensitivity (44%) and high specificity (97%) at the usual CIS-R cut-point of 11/12.
Among primary care attendees the CIDI is a highly valid assessment of common mental disorders, and the CIS-R is moderately valid. Previous studies may have underestimated validity. Against the criteria of all ICD-10 diagnoses (including less severe depressive and anxiety disorders) a much lower CIS-R cut-point is required than that which is usually advocated.
精神病学中使用最广泛的调查工具,即复合国际诊断访谈(CIDI)和修订版临床访谈问卷(CIS-R),所产生的精神疾病发病率估计值存在相当大的差异。人们对这些结构化的非专业访谈评估的有效性提出了质疑。尚未将这些工具的性能与一个共同的既定标准进行直接比较。
总共105名未经挑选的初级保健就诊者在一次就诊中分别接受了CIDI、CIS-R和SCAN访谈,访谈顺序随机。SCAN由一名经过SCAN培训的精神科医生进行,CIDI和CIS-R由一名公共卫生医生进行。对所有ICD-10神经症性障碍的一致性进行了估计。我们使用受试者工作特征(ROC)分析评估了CIS-R发病率量表的总体辨别力。
CIDI对ICD-10诊断的一致性为中等至优秀(kappa = 0.58 - 0.97)。CIS-R的一致性在差到中等之间(kappa = 0.10 - 0.65)。CIS-R发病率量表相对于任何ICD-10障碍的ROC曲线下面积为[0.87(95%CI 0.79 - 0.95)],表明总体辨别力良好,但在CIS-R通常的切点11/12处敏感性较差(44%)而特异性较高(97%)。
在初级保健就诊者中,CIDI对常见精神障碍是一种高度有效的评估工具,而CIS-R的有效性为中等。先前的研究可能低估了其有效性。与所有ICD-10诊断(包括不太严重的抑郁和焦虑障碍)的标准相比,所需的CIS-R切点比通常主张的要低得多。