Cheng Shi-Ming, Liu Er-Yong, DU Xin
National Center for Tuberculosis Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2004 Aug;25(8):655-7.
To study the current status of geriatric tuberculosis (TB) and its impact on TB control program under the directly observed treatment short-course (DOTS) strategy in China.
Using the prevalence information regarding the epidemiology of geriatric TB from the National Random Survey in 2000, a case-control study was carried out to analyze the case detection, treatment and management of geriatric TB patients between DOTS area and non-DOTS area.
The prevalence of sputum smear positive (SS+) in the age group of 65 or above was 440/100 000 which was 3.6 times of the average prevalence of SS+ of all age groups. Geriatric SS+ patients took up 28.8% of all the TB patients in 13 provinces with implementation of DOTS and 28.9% in 15 provinces without. The population of TB case in the age group 65 or above occupied 11.4% of all the newly registered SS+ case in 13 DOTS provinces from 1992 to 2000.
The prevalence of geriatric SS+ was high. In both DOTS and non-DOTS areas, the proportion of geriatric SS+ was high but the registration rate of new SS+ was low among all the age groups. Both high prevalence and low case detection rate of geriatric TB became main issues to be under concern in the TB control strategy in China.
研究中国老年结核病的现状及其对直接观察下的短程治疗(DOTS)策略下结核病控制规划的影响。
利用2000年全国随机调查中有关老年结核病流行病学的患病率信息,开展病例对照研究,分析DOTS地区和非DOTS地区老年结核病患者的病例发现、治疗及管理情况。
65岁及以上年龄组痰涂片阳性(SS+)患病率为440/10万,是所有年龄组SS+平均患病率的3.6倍。在实施DOTS的13个省,老年SS+患者占所有结核病患者的28.8%,在未实施DOTS的15个省占28.9%。1992年至2000年,65岁及以上年龄组的结核病病例数占13个DOTS省份所有新登记SS+病例的11.4%。
老年SS+患病率高。在DOTS地区和非DOTS地区,老年SS+的比例都很高,但在所有年龄组中,新SS+的登记率较低。老年结核病的高患病率和低病例发现率成为中国结核病控制策略中需要关注的主要问题。