Huang Yuesheng, Yang Zongcheng
Professor of Surgery, Director of Staff, Institute of Burn Research, Southwestern Hospital, Third Military Medical University, Chongqing 400038, PR China.
Burns. 2004 Dec;30(8):808-12. doi: 10.1016/j.burns.2004.01.033.
To define the role of measures for preventing early postburn damage in improving the survival rate of burn patients.
12568 burn cases admitted to our institute were chronologically divided into three groups (stages). Total burn surface area (TBSA), survival rate, incidence of burn shock, systemic infection and organ damage as well as the main treatments adopted in the recent decade were analyzed retrospectively.
Incidence of burn shock, systemic infection and organ damage were significantly lower, and the total survival rate and the survival rate in patients with different TBSA were markedly higher in the third stage of the study as compared with those in the first and the second stages. The incidence of organ damage in patients treated with delayed fast fluid infusion, early extensive escharectomy, early enteral feeding, early intervention for inhalation injury and intervention to prevent gut bacterial translocation were also significantly lower than in those without the intervention resources.
Measures for preventing early postburn damage play an important role in improving the survival rate of burn patients.
明确烧伤后早期损伤预防措施在提高烧伤患者生存率方面的作用。
将我院收治的12568例烧伤病例按时间顺序分为三组(阶段)。回顾性分析近十年烧伤总面积(TBSA)、生存率、烧伤休克发生率、全身感染及器官损害情况以及所采取的主要治疗措施。
与第一阶段和第二阶段相比,研究第三阶段烧伤休克、全身感染及器官损害的发生率显著降低,不同TBSA患者的总生存率和生存率明显提高。采用延迟快速补液、早期广泛切痂、早期肠内营养、早期吸入性损伤干预及预防肠道细菌移位干预措施治疗的患者器官损害发生率也显著低于未采取这些干预措施的患者。
烧伤后早期损伤预防措施在提高烧伤患者生存率方面发挥着重要作用。