缬氨霉素在不同溶剂中形成配合物的紫外共振拉曼光谱研究。

UVRR spectroscopic studies of valinomycin complex formation in different solvents.

作者信息

Ozdemir Abdil, Lednev Igor K, Asher Sanford A

机构信息

Department of Chemistry, Faculty of Arts and Sciences, Sakarya University, 54100 Serdivan, Sakarya, Turkey.

出版信息

Spectrochim Acta A Mol Biomol Spectrosc. 2005 Jan 1;61(1-2):19-26. doi: 10.1016/j.saa.2004.03.006.

DOI:10.1016/j.saa.2004.03.006

PMID:15556416

Abstract

We investigated the complexation of valinomycin (VM) in different solvent environments with the aid of the UVRR spectroscopy. By probing the 206.5 and 229 nm excited Raman spectra, we showed that new bands are observed around 1700 and 1290 cm(-1). We assigned the 1700 cm(-1) band to the hydrogen bonded ester carbonyl stretching vibration. In a polar solvent, VM-K(+) complexation shows significant intensity changes in amide and ester carbonyl stretching region. Because of the small amount of conformational interconversion, complexation has a negligible effect on other band intensities including, the amide III, C(alpha)H, and amide II. We also showed the effects of the solvent polarity on the solution conformation of VM.

摘要

我们借助紫外共振拉曼光谱研究了缬氨霉素（VM）在不同溶剂环境中的络合作用。通过探测206.5和229纳米的激发拉曼光谱，我们发现1700和1290厘米⁻¹附近出现了新的谱带。我们将1700厘米⁻¹的谱带归属于氢键酯羰基的伸缩振动。在极性溶剂中，VM-K⁺络合作用在酰胺和酯羰基伸缩区域显示出显著的强度变化。由于构象互变的量很少，络合作用对包括酰胺III、CαH和酰胺II在内的其他谱带强度影响可忽略不计。我们还展示了溶剂极性对VM溶液构象的影响。