Tanoue Yoshihisa, Kado Hideaki, Shiokawa Yuichi, Fusazaki Naoki, Ishikawa Shiro
Department of Cardiovascular Surgery and Pediatric Cardiology, Fukuoka Children's Hospital Medical Center, Fukuoka, Japan.
Ann Thorac Surg. 2004 Dec;78(6):1965-71; discussion 1971. doi: 10.1016/j.athoracsur.2004.06.014.
Midterm and long-term results of patients who underwent a Norwood procedure with a right ventricular-pulmonary artery conduit remain unclear. This study aimed to compare the midterm ventricular performance of the Norwood procedure with right ventricular-pulmonary artery conduit and the Norwood procedure with systemic-pulmonary shunt.
Twenty-one patients who underwent both a bidirectional Glenn procedure and a total cavopulmonary connection after Norwood palliation at Fukuoka Children's Hospital Medical Center were divided into two groups: the systemic-pulmonary shunt group (n = 11) and the right ventricular-pulmonary artery conduit group (n = 10). End-systolic elastance (contractility), effective arterial elastance (afterload), and ventriculoarterial coupling and the ratio of stroke work and pressure-volume area (ventricular efficiency) were measured on the basis of cardiac catheterization data before the bidirectional Glenn procedure, before and after the total cavopulmonary connection, and at approximately 1 year after total cavopulmonary connection.
After bidirectional Glenn procedure and total cavopulmonary connection, end-systolic elastance of the right ventricular-pulmonary artery conduit group was lower than that of the systemic-pulmonary shunt group, whereas effective arterial elastance of the right ventricular-pulmonary artery conduit group was lower than that of the systemic-pulmonary shunt group. Consequently, there was no difference in ventricular efficiency in both groups 1 year after total cavopulmonary connection.
The midterm ventricular performance of the right ventricular-pulmonary artery conduit group was comparable with the systemic-pulmonary shunt group in terms of ventricular efficiency. However, after bidirectional Glenn procedure and total cavopulmonary connection, contractility in patients who underwent a Norwood procedure with a right ventricular-pulmonary artery conduit was inferior to that of patients who underwent a Norwood procedure with a systemic-pulmonary shunt.
接受诺伍德手术并使用右心室-肺动脉导管的患者的中期和长期结果尚不清楚。本研究旨在比较使用右心室-肺动脉导管的诺伍德手术和使用体肺分流的诺伍德手术的中期心室功能。
在福冈儿童医院医疗中心接受诺伍德姑息治疗后又接受双向格林手术和全腔静脉-肺动脉连接术的21例患者被分为两组:体肺分流组(n = 11)和右心室-肺动脉导管组(n = 10)。根据双向格林手术前、全腔静脉-肺动脉连接术前和术后以及全腔静脉-肺动脉连接术后约1年的心脏导管检查数据,测量收缩末期弹性(收缩性)、有效动脉弹性(后负荷)、心室动脉耦合以及每搏功与压力-容积面积之比(心室效率)。
在双向格林手术和全腔静脉-肺动脉连接术后,右心室-肺动脉导管组的收缩末期弹性低于体肺分流组,而右心室-肺动脉导管组的有效动脉弹性低于体肺分流组。因此,全腔静脉-肺动脉连接术后1年两组的心室效率没有差异。
就心室效率而言,右心室-肺动脉导管组的中期心室功能与体肺分流组相当。然而,在双向格林手术和全腔静脉-肺动脉连接术后,接受使用右心室-肺动脉导管的诺伍德手术的患者的收缩性低于接受使用体肺分流的诺伍德手术的患者。