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心脏脂肪瘤:肺动脉压正常时右向左心房分流的罕见原因。

Cardiac lipoma: a rare cause of right-to-left interatrial shunt with normal pulmonary artery pressure.

作者信息

Courtis Javier, Marani Leandro, Amuchastegui Luis Maria, Rodeiro Jose

机构信息

Cardiology Service, Hospital Privado, Cordoba, Argentina.

出版信息

J Am Soc Echocardiogr. 2004 Dec;17(12):1311-4. doi: 10.1016/j.echo.2004.06.031.

Abstract

Cardiac lipomas are rare tumors. They usually remain asymptomatic for a long time and cause angina, arrhythmia, dysfunction of the ventricles or valves, and peripheral embolization during the later stages of development. There is little or no information about right-to-left interatrial shunt with normal pulmonary artery pressure, produced as a consequence of the infiltration of the atrial septum, the right atrial wall, and the myocardium because of the presence of fat in patients with platypnea-orthodeoxia syndrome. We present a patient with this syndrome who was identified through transesophageal echocardiography. The study showed a massive right-to-left shunt without pulmonary hypertension, produced by an important cardiac infiltration of adipose tissue that created a narrow passage in the right atrium, and a redirection of the flow to a patent foramen ovale, explaining the pathophysiology of the syndrome.

摘要

心脏脂肪瘤是罕见的肿瘤。它们通常长期无症状,在疾病发展后期会导致心绞痛、心律失常、心室或瓣膜功能障碍以及外周栓塞。关于平卧位呼吸困难-直立性低氧血症综合征患者因心房隔、右心房壁和心肌受脂肪浸润导致肺动脉压力正常时出现右向左心房分流的信息很少或几乎没有。我们报告一名通过经食管超声心动图确诊的该综合征患者。研究显示,由于脂肪组织对心脏的显著浸润,在右心房形成狭窄通道,并使血流转向卵圆孔未闭,从而产生了无肺动脉高压的大量右向左分流,这解释了该综合征的病理生理机制。

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