Anstey Kaarin J, Butterworth Peter, Jorm Anthony F, Christensen Helen, Rodgers Bryan, Windsor Timothy D
Centre for Mental Health Research, Australian National University, Canberra, ACT 0200, Australia.
J Clin Epidemiol. 2004 Nov;57(11):1202-9. doi: 10.1016/j.jclinepi.2003.11.011.
This study determined whether self-reported Traumatic Brain Injury (TBI), identified in a community sample and occurring up to 60 years previously, is associated with current psychiatric symptoms, suicidality, and psychologic well-being.
Three age cohorts (20-24, 40-44, 60-64) were randomly sampled from the cities of Canberra and Queanbeyan, Australia, yielding a total of 7,485 participants. The samples were administered scales measuring anxiety, depression, suicidality, positive and negative affect, personality traits, and physical health status.
Of the total sample, 5.7% reported history of TBI involving loss of consciousness for at least 15 min, occurring an average of 22 years previously. History of TBI was associated with increased symptoms of depression, anxiety, negative affect, and suicidal ideation.
History of TBI is a risk factor for psychiatric morbidity. The effect is greatest in young adults, and occurs up to several decades subsequent to the occurrence of TBI.
本研究旨在确定在社区样本中自我报告的创伤性脑损伤(TBI),该损伤发生在60年前,是否与当前的精神症状、自杀倾向和心理健康状况相关。
从澳大利亚堪培拉市和昆比恩市随机抽取了三个年龄组(20 - 24岁、40 - 44岁、60 - 64岁),共7485名参与者。对样本进行了测量焦虑、抑郁、自杀倾向、积极和消极情绪、人格特质以及身体健康状况的量表测试。
在总样本中,5.7%报告有TBI病史,其中至少有15分钟意识丧失,平均发生在22年前。TBI病史与抑郁、焦虑、消极情绪和自杀意念的症状增加相关。
TBI病史是精神疾病发病的一个危险因素。这种影响在年轻人中最为显著,且在TBI发生后的几十年内都存在。