Kumagai Masaki, Endo Sohei, Koizumi Fumisada, Kida Akinori, Yamamoto Masahiro
Department of Otolaryngology, Kawaguchi Municipal Medical Center, Kawaguchi 333-0833, Japan.
Auris Nasus Larynx. 2004 Dec;31(4):439-42. doi: 10.1016/j.anl.2004.05.001.
We report a rare case of pleomorphic adenoma arising from the nasal septum. A 32-year-old woman presented with a 3-week-history of left-sided nasal obstruction. Computed tomographic scans revealed an oval mass, measuring about 30 mm in its greatest dimension, in the left anterior nasal cavity. The tumor arose from the anterior part of the nasal septum, and was removed endoscopically with endonasal approach. The microscopic finding showed a lobular and duct-like structures consisting of a loose chondromyxoid stroma. This lesion had histological characteristics of a pleomorphic adenoma, and this was confirmed by immunohistochemical expression of cytokeratin and S-100 protein. Her post-operative course was uneventful, and she is currently free from the disease 8 months after surgery. Diagnosis, clinical behavior and treatment of pleomorphic adenoma of the nasal septum are reviewed from perusal of the literature.
我们报告一例罕见的起源于鼻中隔的多形性腺瘤。一名32岁女性，有3周的左侧鼻塞病史。计算机断层扫描显示在左前鼻腔有一个椭圆形肿块，最大径约30mm。肿瘤起源于鼻中隔前部，采用鼻内镜经鼻入路切除。显微镜下表现为小叶状和导管样结构，由疏松的软骨黏液样间质组成。该病变具有多形性腺瘤的组织学特征，细胞角蛋白和S-100蛋白的免疫组化表达证实了这一点。她的术后过程顺利，术后8个月目前无病生存。通过查阅文献对鼻中隔多形性腺瘤的诊断、临床行为及治疗进行了综述。
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