Meshikhes Abdul-Wahed N, Butt Sohail A, Al-Saihati Basima A
Department of Surgery, Dammam Central Hospital, Dammam, Kingdom of Saudi Arabia.
Saudi Med J. 2004 Nov;25(11):1707-10.
Although the pathological association of thyroid and parathyroid disease is common, the association of both parathyroid adenoma and thyroid cancer is rare. We report here a case of a 45-year-old Saudi woman who was diagnosed to have primary hyperparathyroidism due to a single parathyroid adenoma as confirmed biochemically and radiologically. At operation, the adenoma was found to be an intrathyroid and therefore a thyroid lobectomy was performed. Histology of the excised lobe revealed in addition to the intrathyroid parathyroid adenoma a concurrent occult thyroid papillary carcinoma. This interesting association is discussed based on a literature review.
虽然甲状腺疾病与甲状旁腺疾病在病理上的关联很常见,但甲状旁腺腺瘤与甲状腺癌同时存在的情况却很罕见。我们在此报告一例45岁的沙特女性病例,经生化和影像学检查确诊为单发甲状旁腺腺瘤导致的原发性甲状旁腺功能亢进。手术中发现腺瘤位于甲状腺内,因此进行了甲状腺叶切除术。切除叶的组织学检查显示,除了甲状腺内的甲状旁腺腺瘤外,还同时存在隐匿性甲状腺乳头状癌。本文基于文献综述对这一有趣的关联进行了讨论。