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[使用麦角碱治疗偏头痛后出现的短暂性全面性遗忘症]

[Transient global amnesia following the use of ergots in the treatment of migraine].

作者信息

Gil-Martínez T, Galiano R

机构信息

Unidad de Neurología, Hospital General de Requena, Requena, Valencia, Spain.

出版信息

Rev Neurol. 2004;39(10):929-31.

Abstract

INTRODUCTION

Transient global amnesia (TGA) is defined as a selective, or almost selective, deficit of the memory that appears suddenly and lasts less than 24 hours. The aetiopathogenesis of this syndrome remains unknown and different theories have been put forward about its epileptic or ischemic origin, or the relationship that exists with the neuronal depression that is produced in migraine. A number of triggering factors have been described, including the taking of distinct pharmaceutical preparations.

CASE REPORT

We report the cases of two patients with a history of migraines who suffered TGA after taking ergotamine and dihydroergotamine, respectively, to treat an attack of migraine.

CONCLUSIONS

Given the vasoconstriction effect of these drugs, it was concluded that in both cases the main factor that triggered the TGA was the ingestion of ergots.

摘要

引言

短暂性全面性遗忘症(TGA)被定义为一种突然出现且持续时间少于24小时的选择性或几乎选择性的记忆缺陷。该综合征的病因发病机制尚不清楚,关于其癫痫或缺血性起源,或与偏头痛中产生的神经元抑制之间的关系,已经提出了不同的理论。已经描述了一些触发因素,包括服用不同的药物制剂。

病例报告

我们报告了两名有偏头痛病史的患者的病例,他们分别在服用麦角胺和二氢麦角胺治疗偏头痛发作后发生了TGA。

结论

鉴于这些药物的血管收缩作用,得出的结论是,在这两个病例中,触发TGA的主要因素是麦角的摄入。

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