Yajima Aiji, Ogawa Yoshihide
Towa Hospital, Department of Urology.
Clin Calcium. 2004 May;14(5):727-30.
Bone histomorphometry is essential to diagnosis of renal osteodystrophy. Sherrard et al classified renal osteodystrophy into the 5 groups according to Fb.V/TV, OV/BV and BFR/TV of cancellous bone (Osteitis fibrosa, Mixed uremic osteodystrophy, Osteomalacia, Mild lesion, Aplastic disease). In addition, because endocortical bone loss is generally irreversible, the evaluation of this region in the transiliac bone biopsy specimen also seems to be important.
骨组织形态计量学对于肾性骨营养不良的诊断至关重要。谢拉德等人根据松质骨的骨小梁体积分数(Fb.V/TV)、骨体积分数(OV/BV)和骨形成率(BFR/TV)将肾性骨营养不良分为5组(纤维性骨炎、混合性尿毒症骨营养不良、骨软化症、轻度病变、再生障碍性疾病)。此外,由于皮质内骨丢失通常是不可逆的,因此在髂骨活检标本中对该区域进行评估似乎也很重要。