Yumita Shigeru
Department of nephroendocrinology, Kojinkai Central Hospital.
Clin Calcium. 2004 May;14(5):771-7.
Management of hyperphosphatemia in hemodialysis patients is very important to prevent progress of renal hyperparathyroidism or ectopic calcification. Sevelamer hydrochloride is a Ca and Al free phosphate binder, and reduces serum phosphorus level, without any influence on serum Ca level, and Ca-P products. This compound is expected to reduce the incidence of arterial calcification, and improve the QOL (quality of life) of hemodialysis patients.
控制血液透析患者的高磷血症对于预防肾性甲状旁腺功能亢进的进展或异位钙化非常重要。盐酸司维拉姆是一种不含钙和铝的磷结合剂,可降低血清磷水平,而对血清钙水平和钙磷乘积没有任何影响。预计这种化合物可降低动脉钙化的发生率,并改善血液透析患者的生活质量。