Michigami Toshimi
Department of Environmental Medicine, Osaka Medical Center and Research Institute for Maternal and Child Health.
Clin Calcium. 2004 Jun;14(6):64-9.
The effects of 1,25 (OH) (2)D on bone mineralization appear to be indirect by stimulating the calcium and phosphate supply, mainly by absorption from intestine. The disturbance in vitamin D action results in rickets in infancy and osteomalacia in adults. An association has been recently reported between mild vitamin D insufficiency and decreased bone mineral density in the elderly, which enhances the importance of appropriate vitamin D intake.
1,25(OH)₂D对骨矿化的影响似乎是间接的,主要通过刺激钙和磷的供应,主要是通过肠道吸收。维生素D作用的紊乱会导致婴儿期佝偻病和成人期骨软化症。最近有报道称,老年人轻度维生素D缺乏与骨密度降低之间存在关联,这凸显了适当摄入维生素D的重要性。