Newsom Richard S B, Johnston Robert, Sullivan Paul M, Aylward G Bill, Holder Graham E, Gregor Zdenek J
Department of Vitreoretinal Surgery, Moorfields Eye Hospital, London, England.
Retina. 2004 Dec;24(6):871-7. doi: 10.1097/00006982-200412000-00005.
Removal of silicone oil after vitreoretinal surgery reduces potential complications of glaucoma and cataract and improves visual function in 30% of patients. We report the clinical findings of a series of patients who experienced unexpected and permanent visual loss after removal of silicone oil.
Seven patients with visual loss after removal of silicon oil were investigated with best-corrected Snellen visual acuity (BCVA) assessment, fundus biomicroscopy, fluorescein angiography, optical coherence tomography, and electrophysiologic examination.
Six men and one woman (average age, 42.8 years.) presented with profound BCVA loss, averaging 4.7 Snellen lines (SD 1.4), after silicon oil removal. No other complications associated with oil removal were noted. The retina remained attached in all cases, no patient developed cystoid macular edema or epiretinal membrane, and optical coherence tomographic and fluorescein angiographic findings remained normal. Electrodiagnostic testing showed a range of abnormalities, with the majority of patients showing severe macular dysfunction.
We describe a new phenomenon of unexpected visual loss after oil removal in patients with good visual potential. The pathogenesis remains obscure.
玻璃体视网膜手术后取出硅油可降低青光眼和白内障的潜在并发症,并使30%的患者视力功能得到改善。我们报告了一系列在取出硅油后意外发生永久性视力丧失患者的临床研究结果。
对7例取出硅油后视力丧失的患者进行了最佳矫正视力(BCVA)评估、眼底生物显微镜检查、荧光素血管造影、光学相干断层扫描和电生理检查。
6名男性和1名女性(平均年龄42.8岁)在取出硅油后出现了明显的BCVA下降,平均下降4.7行Snellen视力表视力(标准差1.4)。未发现与取油相关的其他并发症。所有病例视网膜均保持附着,无患者发生黄斑囊样水肿或视网膜前膜,光学相干断层扫描和荧光素血管造影结果均正常。电诊断测试显示一系列异常,大多数患者表现为严重的黄斑功能障碍。
我们描述了一种在视力潜能良好的患者中取出硅油后意外视力丧失的新现象。其发病机制仍不清楚。