敌意对非裔美国和白人青年成年人的心血管危险因素具有不同的预测作用。

Hostility differentially predicts cardiovascular risk factors in African American and White young adults.

作者信息

Cooper Denise C, Waldstein Shari R

机构信息

Department of Psychology, University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, USA.

出版信息

J Psychosom Res. 2004 Nov;57(5):491-9. doi: 10.1016/j.jpsychores.2004.02.017.

DOI:10.1016/j.jpsychores.2004.02.017

PMID:15581654

Abstract

OBJECTIVE

Hostility may influence racial disparities in cardiovascular disease through differential associations with cardiovascular risk factors. This study explored racial variations in relations between hostility and selected cardiovascular risk factors.

METHODS

Cook-Medley Hostility (Ho) scores and 11 risk factors were examined among 66 healthy, White and African American young adults.

RESULTS

Controlling for age, gender, and body mass index, the interaction of hostility and race yielded significant (or marginal) associations with resting systolic and diastolic blood pressure (SBP, DBP), cardiac index (CI; i.e. cardiac output adjusted for body size), total peripheral resistance (TPR), insulin (INS), triglycerides (TG) and percent body fat (PBF). Contributing substantial variance, hostility was positively associated with SBP, DBP, TPR, TG and INS, and negatively associated with CI among African Americans. Conversely, hostility was negatively associated with TPR and PBF among Whites.

CONCLUSION

Hostility may confer greater cardiovascular risk among young African Americans than Whites.

摘要

目的

敌意可能通过与心血管危险因素的不同关联影响心血管疾病的种族差异。本研究探讨了敌意与选定心血管危险因素之间关系的种族差异。

方法

对66名健康的白人和非裔美国年轻成年人进行了库克-梅德利敌意（Ho）评分及11种危险因素的检测。

结果

在控制年龄、性别和体重指数后，敌意与种族的交互作用与静息收缩压和舒张压（SBP、DBP）、心脏指数（CI；即根据体型调整的心输出量）、总外周阻力（TPR）、胰岛素（INS）、甘油三酯（TG）和体脂百分比（PBF）存在显著（或边缘）关联。在非裔美国人中，敌意对变异的贡献很大，与SBP、DBP、TPR、TG和INS呈正相关，与CI呈负相关。相反，在白人中，敌意与TPR和PBF呈负相关。