Germain Michel A, Marandas Patrick, Dubousset Jean, Mascard Eric, Legagneux Josette
Département de Chirurgie Cervico-Faciale, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif cedex.
Bull Acad Natl Med. 2004;188(3):441-55; discussion 455-8.
Free-tissue transfer has become an accepted method for reconstructing complex surgical defects. We review 25 years' experience of this approach. In France, microsurgery was first performed in 1974. I myself constructed 839 consecutive free flaps in 821 patients during a 25-year period. Here we distinguish between two different indications, namely malignant and benign lesions. In oncology, the patient recovers good quality of life even if the prognosis is poor. In contrast, the transplant offers permanent cure for patients with benign lesions. Microvascular anastomoses were constructed with separated stitches (90% of anastomoses); end-to-end anastomoses were preferred (85%). Manual suture with thread is the best technique. Post-operative flap monitoring included clinical observation, Doppler sonography, thermic probing, and endoscopy. The overall success rate of free flap reconstruction was 95.5%. In cancer patients, surviving flaps resulted in wound healing and did not delay post-operative irradiation or chemotherapy. The incidence of major complications (death 0.36%, necrosis 4.5%) and minor post operative complications (27.1%) was acceptable. The mean hospital stay was 20 days. Careful selection of the transplants yielded good reliability. Six donor sites were sufficient to reconstruct the majority of defects. Teaching of microsurgery is one of our main preoccupations. This is an indispensable technique in all fields of reconstruction. Rigorous training is necessary and much time must be spent before reaching a high level of reliability.
游离组织移植已成为修复复杂手术缺损的一种公认方法。我们回顾了采用这种方法25年的经验。在法国,显微外科手术于1974年首次开展。在25年的时间里,我本人连续为821例患者构建了839个游离皮瓣。在此,我们区分两种不同的适应症,即恶性和良性病变。在肿瘤学领域,即使预后不佳,患者的生活质量也能得到改善。相比之下,移植为良性病变患者提供了根治方法。微血管吻合采用间断缝合(占吻合术的90%);端端吻合更受青睐(占85%)。手工丝线缝合是最佳技术。术后皮瓣监测包括临床观察、多普勒超声检查、热探测和内镜检查。游离皮瓣重建的总体成功率为95.5%。在癌症患者中,存活的皮瓣实现了伤口愈合,且未延迟术后放疗或化疗。严重并发症(死亡率0.36%,坏死率4.5%)和术后轻微并发症(发生率27.1%)的发生率是可以接受的。平均住院时间为20天。精心选择移植组织可获得良好的可靠性。六个供区足以修复大多数缺损。显微外科教学是我们的主要关注点之一。这是所有重建领域不可或缺的技术。必须进行严格培训,且要花费大量时间才能达到较高的可靠性水平。