Suppr超能文献

用于药物研发的连续流动微反应器。

Continuous flow microreactors for drug discovery.

作者信息

Watts Paul

机构信息

University of Hull, Department of Chemistry, Hull, UK.

出版信息

Curr Opin Drug Discov Devel. 2004 Nov;7(6):807-12.

Abstract

This article reviews the use of microreactors in the field of organic and combinatorial synthesis with regard to drug discovery applications. Research conducted into microreactors that enable in situ purification is described, and it is proposed that compounds could potentially be screened within an integrated bioassay system. A description of how it would be possible to use this technology to prepare larger quantities of pharmaceutical intermediates is also given.

摘要

本文综述了微反应器在有机合成和组合合成领域中在药物发现应用方面的使用情况。描述了对能够进行原位纯化的微反应器的研究,并提出化合物有可能在集成生物测定系统内进行筛选。还介绍了如何利用该技术制备大量药物中间体。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验