眼内手术后数十年上皮内生的发展。
Development of epithelial downgrowth several decades after intraocular surgery.
作者信息
Kim Shane K, Ibarra Michael S, Syed Nasreen A, Sulewski Michael E, Orlin Stephen E
机构信息
Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
出版信息
Cornea. 2005 Jan;24(1):108-9. doi: 10.1097/01.ico.0000134188.96245.1b.
PURPOSE
To report the management of a patient with the longest reported interval between intraocular surgery and the development of epithelial downgrowth.
METHODS
A 53-year-old man who underwent right eye penetrating keratoplasty in 1970 for keratoconus and removal of an iris cyst in 1977 developed epithelial downgrowth 25 years after cyst removal.
RESULTS
The area of epithelial downgrowth was initially treated with cryotherapy. Two weeks postoperatively, the patient had no resolution of epithelial downgrowth and developed diffuse corneal edema. Penetrating keratoplasty was performed along with extracapsular cataract extraction. At 6 months of follow-up, the patient's graft was clear, without evidence of recurrence of epithelial downgrowth, and he had 20/50 visual acuity.
CONCLUSION
Epithelial downgrowth is an uncommon yet serious complication of intraocular surgery, making early detection of this condition important. This case illustrates that epithelial downgrowth can occur several decades after intraocular surgery.
目的
报告一例眼内手术后至上皮内生发生的间隔时间为报道中最长的患者的治疗情况。
方法
一名53岁男性，1970年因圆锥角膜接受右眼穿透性角膜移植术，1977年摘除虹膜囊肿，囊肿摘除25年后发生上皮内生。
结果
上皮内生区域最初采用冷冻疗法治疗。术后两周，患者上皮内生未消退，并发弥漫性角膜水肿。遂行穿透性角膜移植术联合白内障囊外摘除术。随访6个月时，患者移植片透明，无上皮内生复发迹象，视力为20/50。
结论
上皮内生是眼内手术一种罕见但严重的并发症，因此早期发现该病很重要。本病例表明，上皮内生可在眼内手术后数十年发生。
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