Vishnevskaia E E
Vopr Onkol. 2004;50(4):440-3.
The paper is concerned with certain peculiar relationships between tumor and body in 150 endometrial carcinoma patients of 45 years or younger. Metabolic and generative disorders were detected in 70%. Such disturbances as chronic anovulation (80%). infertility and/or ovarian polycystosis (32%) were identified. They developed prior to neoplastic alterations had taken place and promoted various hyperplastic processes in the endometrium which are generally detectable in 70%. The most frequent localization of endometrial carcinoma was tubular angle area (76.9%). Lack of symptoms in some patients was due to the absence of morphological evidence on invasion into myometrial stroma (68.7%). We identified typical predisposition to endometrial carcinoma as well as an optimal sequence of cytological, ultrasound, endoscopic and morphological procedures which might help detect the disease in younger women at an early stage.
本文关注150例45岁及以下子宫内膜癌患者肿瘤与身体之间的某些特殊关系。70%的患者检测到代谢和生殖紊乱。发现了诸如慢性无排卵(80%)、不孕和/或卵巢多囊症(32%)等紊乱情况。这些情况在肿瘤性改变发生之前就已出现,并促进了子宫内膜的各种增生过程,这种增生过程通常在70%的患者中可检测到。子宫内膜癌最常见的部位是输卵管角区域(76.9%)。一些患者没有症状是由于缺乏侵入肌层基质的形态学证据(68.7%)。我们确定了子宫内膜癌的典型易患因素以及细胞学、超声、内镜和形态学检查的最佳顺序,这可能有助于在年轻女性中早期发现该疾病。