MacCormack Mollie A, Cohen Lisa M, Rogers Gary S
Department of Dermatology, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.
Dermatol Surg. 2004 Dec;30(12 Pt 2):1533-8. doi: 10.1111/j.1524-4725.2004.30562.x.
The current medical literature contains multiple different meanings for the term "local melanoma recurrence." Confusion regarding locally persistent and locally metastatic disease makes interpretation and analysis of previously published reports difficult if not impossible.
The objective was to present a more precise definition of local melanoma recurrence.
A case is reported and the literature is reviewed.
Owing to the myriad of different definitions that exist in the medical literature, the term "local melanoma recurrence" is ambiguous and at times misleading. Melanoma that recurs locally from persistence of tumor at the resection margins has a vastly different prognosis than recurrence developing from local (satellite) metastases adjacent to the surgical resection site. We propose the use of the terms "persistent melanoma" and "local metastasis" as more precise and predictive of a patient's prognosis.
当前医学文献中“局部黑色素瘤复发”一词有多种不同含义。局部持续存在和局部转移疾病之间的混淆使得对先前发表报告的解读和分析即便不是不可能,也是困难的。
目的是给出更精确的局部黑色素瘤复发定义。
报告一例病例并复习文献。
由于医学文献中存在大量不同定义,“局部黑色素瘤复发”一词含混不清,有时还会产生误导。肿瘤在切除边缘持续存在而局部复发的黑色素瘤与手术切除部位附近局部(卫星灶)转移所致复发的预后截然不同。我们建议使用“持续性黑色素瘤”和“局部转移”这两个术语,因为它们更精确,且能更好地预测患者预后。