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[缓释药物或肠溶包衣药物:它们使用正确吗?]

[Delayed-release drugs or with enteric cover: are they correctly used?].

作者信息

Vidal Miquel A, Benet Català A, Ortín Font F, Caelles Franch N

机构信息

Servicio de Farmacia, Pius Hospital de Valls, Valls, Tarragona, Spain.

出版信息

Aten Primaria. 2004 Dec;34(10):541-7. doi: 10.1016/s0212-6567(04)70860-4.

Abstract

OBJECTIVES

To estimate the prevalence of the correct use of a group of oral drugs, which must keep the integrity of their pharmaceutical pattern at the moment of taking them, by the population who uses them.

DESIGN

A transversal and descriptive study based on observation, by means of a questionnaire, which evaluated how the interviewees used the drugs.

SETTING

Twenty-eight communal chemists.

PARTICIPANTS

Patients who came up to the chemist to get drugs included in the study.

MEASURES AND RESULTS

612 questionnaires were evaluated. It was detected that the 7% (95% CI, 5.1-9.2) of the interviewees chewed or grinded the delayed release drugs or with enteric cover, and the 72% (95% CI, 68.7-75.8) made at least one mistake when using these drugs. The most frequent errors were related to the conservation and the intake of the drug related to the food. No relation between the reading of the patient information leaflet and the correct use of these drugs has been observed.

CONCLUSIONS

Due to the high percentage of interviewees who use drugs incorrectly, we believe that every health professional should provide the drug users with oral and written information on how to handle such drugs, specifically emphasizing how to use them and where to keep them.

摘要

目的

评估一组服用时必须保持药剂形态完整的口服药物在使用者中的正确使用率。

设计

基于观察的横断面描述性研究,通过问卷调查评估受访者使用药物的方式。

地点

28家社区药店。

参与者

到药店领取纳入研究药物的患者。

措施与结果

共评估了612份问卷。发现7%(95%可信区间,5.1 - 9.2)的受访者咀嚼或研磨缓释药物或肠溶包衣药物,72%(95%可信区间,68.7 - 75.8)的受访者在使用这些药物时至少犯了一个错误。最常见的错误与药物保存以及与食物相关的服药方式有关。未观察到患者信息手册的阅读与这些药物的正确使用之间存在关联。

结论

鉴于不正确使用药物的受访者比例很高,我们认为每位卫生专业人员都应向药物使用者提供关于如何处理此类药物的口头和书面信息,特别强调如何使用以及何处保存这些药物。

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本文引用的文献

1
Drug interactions with grapefruit juice.
Med Lett Drugs Ther. 2004 Jan 5;46(1173):2-4.
4
Patient information leaflets--helpful guidance or a source of confusion?
Pharmacoepidemiol Drug Saf. 2003 Jan-Feb;12(1):55-9. doi: 10.1002/pds.795.
6
Grapefruit juice: potential drug interactions.
CMAJ. 2002 Aug 6;167(3):279-80.
7
Patients' knowledge and perceptions of the side-effects of OTC medication.
J Clin Pharm Ther. 2002 Aug;27(4):243-8. doi: 10.1046/j.1365-2710.2002.00416.x.
8
Food-drug interactions.
Drugs. 2002;62(10):1481-502. doi: 10.2165/00003495-200262100-00005.
9
Clinical pharmacy services, hospital pharmacy staffing, and medication errors in United States hospitals.
Pharmacotherapy. 2002 Feb;22(2):134-47. doi: 10.1592/phco.22.3.134.33551.
10
Drug-nutrient interactions: a review.
AACN Clin Issues. 2000 Nov;11(4):580-9. doi: 10.1097/00044067-200011000-00009.

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