Suppr超能文献

[轻度认知障碍]

[Mild cognitive impairment].

作者信息

Gimzal Aylan, Yazgan Cağri

出版信息

Turk Psikiyatri Derg. 2004 Winter;15(4):309-16.

Abstract

It is essential to determine whether memory impairment is accompanied by impairment in other cognitive areas in patients presenting with the complaint of forgetfulness. Furthermore, it should be established whether this impairment is associated with normal aging or dementia. Several terms have been suggested to identify cognitive disorders without dementia. Benign senescent forgetfulness, age-associated memory impairment and aging-associated cognitive decline are considered to fall within the limits of normal aging. A recently proposed term, mild cognitive impairment, as opposed to the terms mentioned above, identifies a transitional state between normal aging and dementia. With the use of criteria proposed for mild cognitive impairment, this disorder converts to Alzheimer's disease at a rate of 10-15 % yearly. However, in longitudinal studies different neuropsychological tests and assessment scales were used for the diagnosis of mild cognitive impairment, resulting in different conversion rates to Alzheimer's disease. Recently, it has been proposed to classify mild cognitive impairment according to memory and non-memory involvement as amnestic, multiple domain and non-memory single domain clinical subtypes. Furthermore, vascular, metabolic, traumatic and various etiologies other than degenerative etiology are mentioned. Besides the medications known to be effective for cognitive dysfunctions, memory enhancement training is suggested for treatment. A consensus on the diagnostic criteria for mild cognitive impairment, determining the subgroups and further studies on treatment are necessary.

摘要

对于主诉健忘的患者,确定记忆障碍是否伴有其他认知领域的损害至关重要。此外,还应确定这种损害是与正常衰老还是痴呆相关。已经提出了几个术语来识别无痴呆的认知障碍。良性衰老性健忘、年龄相关性记忆损害和衰老相关性认知衰退被认为在正常衰老范围内。与上述术语不同,最近提出的术语“轻度认知障碍”识别出正常衰老和痴呆之间的过渡状态。使用针对轻度认知障碍提出的标准,这种疾病每年以10% - 15%的速率转变为阿尔茨海默病。然而,在纵向研究中,不同的神经心理学测试和评估量表被用于诊断轻度认知障碍,导致转变为阿尔茨海默病的速率不同。最近,有人提议根据记忆和非记忆受累情况将轻度认知障碍分为遗忘型、多领域型和非记忆单领域型临床亚型。此外,还提到了血管性、代谢性、创伤性以及退行性病因以外的各种病因。除了已知对认知功能障碍有效的药物外,还建议进行记忆增强训练作为治疗方法。有必要就轻度认知障碍的诊断标准、确定亚组以及进一步的治疗研究达成共识。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验