Visockiene Ramūne, Inciūra Artūras, Juozaityte Elona
Clinic of Oncology, Kaunas University of Medicine, Lithuania.
Medicina (Kaunas). 2004;40(12):1239-48.
The main objective of this review is to present various types of treatment which are available for patients with bladder cancer. Some treatments are standard and some are being tested in clinical trials. Nowadays we have a lot of new treatment approaches and can use them for bladder cancer treatment. For superficial bladder cancer the main treatment method is operation. Adjuvant chemotherapy is indicated only for high-risk patients and the tumor recurrence rate is decreased to about 20%. Surgery and radiotherapy is used for muscle-invasive bladder cancer. There are no clear indications for neoadjuvant treatment administration. Radiotherapy and chemotherapy are suitable after no radical operation. Administration of palliative chemotherapy for metastatic disease might improve survival. We have to use different methods of treatment (operation, chemotherapy, radiotherapy, biology therapy) as multimodality treatment option for bladder cancer.
本综述的主要目的是介绍膀胱癌患者可采用的各类治疗方法。有些治疗方法是标准疗法,有些则正在临床试验中接受检验。如今我们有许多新的治疗方法,可将其用于膀胱癌治疗。对于浅表性膀胱癌,主要治疗方法是手术。辅助化疗仅适用于高危患者,肿瘤复发率可降至约20%。手术和放疗用于肌层浸润性膀胱癌。新辅助治疗的应用尚无明确指征。无法进行根治性手术时,放疗和化疗是合适的选择。对转移性疾病进行姑息化疗可能会提高生存率。我们必须采用不同的治疗方法(手术、化疗、放疗、生物治疗)作为膀胱癌的多模式治疗选择。