T cell : B cell collaboration--the response to polysaccharide antigens.
作者信息
Rosen F S
机构信息
The Center of Blood Research, Boston, MA 02115, USA.
出版信息
Semin Immunol. 1989 Sep;1(1):87-91.
PMID:15630962
Abstract
The humoral response to polysaccharide antigens occurs as a result of T cell-B cell collaboration that is very different from the present understanding of the mechanisms whereby protein antigens are taken up, processed and exposed on the cell membrane in the context of MHC class II molecules in a manner suitable for recognition by a T cell antigen receptor. Two models, Wiskott-Aldrich syndrome and CBA/N mice bearing the xid mutation, are examined because in both cases there is a failure to respond to polysaccharide antigens.
摘要
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T cell : B cell collaboration--the response to polysaccharide antigens.
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