Foley Kathleen A, Vasey Joseph, Berra Kathleen, Alexander Charles M, Markson Leona E
Outcomes Research & Management, US Medical & Scientific Affairs, Merck & Co, Inc, West Point, PA 19468, USA.
J Cardiovasc Nurs. 2005 Jan-Feb;20(1):35-42. doi: 10.1097/00005082-200501000-00008.
Patient adherence with cholesterol-lowering medications is a crucial component in helping patients achieve lipid goals. Understanding patient attitudes and beliefs about hyperlipidemia and its pharmacological treatments may be useful in improving patient adherence with their treatment plan. The objectives of this study were to develop a theoretically based, statistically reliable, and valid survey instrument for measuring the attitudes and beliefs of patients towards hyperlipidemia and its treatments, and to determine whether the attitudes measured were associated with patient-reported medication adherence. We assessed the reliability of the instrument through an examination of the internal consistency and factor structure of 8 attitude constructs including attitudes about the effectiveness of medications and the quality of doctor-patient communication. Validity was assessed through correlations among the attitudes and the relationship between the attitudes and the number of medication adherence problems the patient experienced in the past month. Internal consistency scores for the 8 constructs ranged from .46 to .82. Factor loadings indicated that the individual items belonged to their respective constructs, as hypothesized. The validity of the instrument was demonstrated by significant relationships between 4 of the attitudinal constructs and self-reported medication adherence problems. This study provides preliminary evidence of the reliability and validity of the HABIT (Hyperlipidemia: Attitudes and Beliefs in Treatment) patient survey of attitudes about the treatment of hyperlipidemia.
患者对降胆固醇药物的依从性是帮助患者实现血脂目标的关键因素。了解患者对高脂血症及其药物治疗的态度和信念可能有助于提高患者对治疗方案的依从性。本研究的目的是开发一种基于理论、统计可靠且有效的调查工具,用于测量患者对高脂血症及其治疗的态度和信念,并确定所测量的态度是否与患者报告的药物依从性相关。我们通过检查包括对药物疗效和医患沟通质量的态度在内的8种态度结构的内部一致性和因子结构,评估了该工具的可靠性。通过态度之间的相关性以及态度与患者在过去一个月中经历的药物依从性问题数量之间的关系来评估有效性。8种结构的内部一致性得分范围为0.46至0.82。因子载荷表明,各个项目如假设的那样属于各自的结构。该工具的有效性通过4种态度结构与自我报告的药物依从性问题之间的显著关系得到证明。本研究为HABIT(高脂血症:治疗中的态度和信念)患者对高脂血症治疗态度调查的可靠性和有效性提供了初步证据。