Suppr超能文献

[胃癌辅助治疗的新见解]

[New insights in the adjuvant treatment of gastric cancer].

作者信息

Jansen E P M, Boot H, Cats A, van Coevorden F, Zoetmulder F A N, Verheij M

机构信息

Afd. Radiotherapie, Het Nederlands Kanker Instituut/Antoni van Leeuwenhoek Ziekenhuis, Plesmanlaan 121, 1066 CX Amsterdam.

出版信息

Ned Tijdschr Geneeskd. 2004 Dec 18;148(51):2529-34.

Abstract

The current standard treatment of patients with gastric cancer is partial or total stomach resection and dissection of the draining lymph nodes. This approach, however, results in a rather low survival rate, partly because the diagnosis is often established in an advanced stage. Various strategies, including adjuvant radiotherapy, chemotherapy or more extensive surgical procedures, have resulted mainly in increased morbidity without improving survival. In a recent randomised trial, concurrent postoperative radiotherapy and chemotherapy prolonged survival and reduced the chance of a local recurrence at an acceptable toxicity. Although several aspects of combined radiochemotherapy require further study, this new treatment concept appears to be a promising addition to the therapeutic arsenal for gastric cancer.

摘要

目前,胃癌患者的标准治疗方法是部分或全胃切除及引流淋巴结清扫。然而,这种方法导致的生存率相当低,部分原因是诊断往往在晚期才得以确立。包括辅助放疗、化疗或更广泛的外科手术在内的各种策略,主要导致发病率增加,而未提高生存率。在最近一项随机试验中,术后同步放化疗延长了生存期,并在可接受的毒性水平下降低了局部复发的几率。尽管放化疗联合治疗的几个方面仍需进一步研究,但这种新的治疗理念似乎是胃癌治疗手段中有前景的补充。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验