Takano-Lee Miwa, Edman John D, Mullens Bradley A, Clark John M
Center for Vector-Borne Diseases, University of California, Davis, CA, USA.
J Pediatr Nurs. 2004 Dec;19(6):393-8. doi: 10.1016/j.pedn.2004.11.002.
As the frequency and level of pediculicide resistance increases throughout the world, the need for novel solutions to control pediculosis has intensified. The development and registration of new pesticides has become so costly that many chemical companies are unwilling to pursue it and health-care providers now face a serious lack of new commercial pediculicides. Many infested people resort to using "home-remedy" approaches that have not been scientifically tested. In this article, we examined the potential value of six purportedly effective "home remedies" (vinegar, isopropyl alcohol, olive oil, mayonnaise, melted butter, and petroleum jelly) to treat head louse infestations and the likelihood of drowning lice by water submersion. Results indicated that only the application of petroleum jelly caused significant louse mortality but no treatment prevented lice from laying eggs. Most home remedy products did little to kill eggs, despite prolonged exposure. Petroleum jelly caused the greatest egg mortality, allowing only 6% to hatch. It was extremely difficult to drown lice, despite extended periods (i.e., 8 hr) of water submersion, suggesting that killing lice by depriving them of oxygen is inefficient. None of the home remedy products we surveyed was an effective means of louse control. This suggests that when treatment failure occurs, an increased amount of time and effort should be focused on alternative chemical pediculicides and/or manual louse removal (i.e., combing) rather than using any of these products.
随着全球范围内抗虱剂耐药性的频率和水平不断增加,控制头虱病的新解决方案的需求也日益迫切。新农药的研发和注册成本变得如此高昂,以至于许多化学公司都不愿涉足,医疗保健提供者现在面临着新的商用抗虱剂严重短缺的问题。许多受感染的人诉诸于使用未经科学检验的“家庭疗法”。在本文中,我们研究了六种据称有效的“家庭疗法”(醋、异丙醇、橄榄油、蛋黄酱、融化的黄油和凡士林)治疗头虱感染的潜在价值以及通过水浸淹死虱子的可能性。结果表明,只有涂抹凡士林会导致显著的虱子死亡率,但没有一种疗法能阻止虱子产卵。尽管长时间接触,大多数家庭疗法产品对杀死虱卵几乎没有效果。凡士林导致的虱卵死亡率最高,只有6%孵化。尽管长时间(即8小时)水浸,淹死虱子极其困难,这表明通过剥夺虱子氧气来杀死它们效率低下。我们调查的家庭疗法产品中没有一种是控制虱子的有效方法。这表明,当治疗失败时应将更多时间和精力集中在替代化学抗虱剂和/或手动去除虱子(即梳篦)上,而不是使用这些产品中的任何一种。