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腕管综合征中神经传导速度测量的敏感性、特异性和变异性。

Sensitivity, specificity, and variability of nerve conduction velocity measurements in carpal tunnel syndrome.

作者信息

Lew Henry L, Date Elaine S, Pan Steven S, Wu Peter, Ware Paul F, Kingery Wade S

机构信息

Physical Medicine and Rehabilitation Service, VA Palo Alto Health Care System, Palo Alto, CA 94304, USA.

出版信息

Arch Phys Med Rehabil. 2005 Jan;86(1):12-6. doi: 10.1016/j.apmr.2004.03.023.

DOI:10.1016/j.apmr.2004.03.023
PMID:15640982
Abstract

OBJECTIVE

To explore the diagnostic values of 8 commonly used electrodiagnostic techniques for measuring median nerve conduction velocity (NCV) in carpal tunnel syndrome (CTS).

DESIGN

Sensitivity and specificity analyses.

SETTING

A hospital-based electrodiagnostic laboratory.

PARTICIPANTS

Forty-four normal hands and 136 symptomatic hands.

INTERVENTIONS

Not applicable.

MAIN OUTCOME MEASURES

(1) Long-segment studies: antidromic wrist-to-digit sensory NCV without subtraction, (2) short-segment studies: transcarpal palm-to-wrist mixed NCV without subtraction, and (3) 2 segment studies: antidromic transcarpal sensory NCV with subtraction (differential calculation from wrist-to-digit and palm-to-digit segments). Both onset and peak latency values were obtained for calculating the NCV. Sensitivity, specificity, and coefficient of variance were calculated for each NCV study.

RESULTS

The short-segment, onset latency-based transcarpal mixed NCV yielded the highest sensitivity (75%).

CONCLUSIONS

Results from measurement of a single, short-nerve segment tended to be superior to results obtained by either long-segment studies or differential subtraction between 2 segments of the same nerve in the electrodiagnosis of CTS. Explanations for our results are offered from both electrophysiologic and statistical perspectives.

摘要

目的

探讨8种常用电诊断技术在测量腕管综合征(CTS)正中神经传导速度(NCV)方面的诊断价值。

设计

敏感性和特异性分析。

地点

一家医院的电诊断实验室。

参与者

44只正常手和136只出现症状的手。

干预措施

不适用。

主要观察指标

(1)长节段研究:无减法的顺行性腕至指感觉NCV,(2)短节段研究:无减法的经腕掌至腕混合NCV,以及(3)双节段研究:有减法的顺行经腕感觉NCV(腕至指节段和掌至指节段的差值计算)。计算NCV时获取起始潜伏期和峰值潜伏期值。计算每项NCV研究的敏感性、特异性和变异系数。

结果

基于起始潜伏期的短节段经腕混合NCV敏感性最高(75%)。

结论

在CTS的电诊断中,单一短神经节段测量结果往往优于长节段研究或同一神经两个节段之间的差值减法测量结果。从电生理和统计学角度对我们的结果进行了解释。

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