Vorona Robert D, Winn Maria P, Babineau Teresa W, Eng Benjamin P, Feldman Howard R, Ware J Catesby
Division of Sleep Medicine, Departments of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
Arch Intern Med. 2005 Jan 10;165(1):25-30. doi: 10.1001/archinte.165.1.25.
Insufficient sleep and obesity are common in the United States. Restricted sleep causes important neurocognitive changes, including excessive daytime sleepiness and altered mood. This may result in work-related injuries and automotive crashes. Evidence links sleep loss to hormonal changes that could result in obesity. This article examines the association between restricted sleep and obesity in a heterogeneous adult primary care population.
A total of 1001 patients from 4 primary care practices participated in this prospective study. Patients completed a questionnaire administered by a nurse or study coordinator concerning demographics, medical problems, sleep habits, and sleep disorders. Professional staff measured height and weight in the office. The relationship between body mass index (BMI) and reported total sleep time per 24 hours was analyzed after categorizing patients according to their BMI (calculated as weight in kilograms divided by the square of height in meters) as being of normal weight (<25), overweight (25-29.9), obese (30-39.9), or extremely obese (> or =40).
Analyzable forms from 924 patients aged between 18 and 91 years indicated that (1) the mean BMI was 30; (2) women slept more than men; (3) overweight and obese patients slept less than patients with a normal BMI (patients reported less sleep in a nearly linear relationship from the normal through the obese group); and (4) this trend of decreasing sleep time was reversed in the extremely obese patients.
This study found that reduced amounts of sleep are associated with overweight and obese status. Interventions manipulating total sleep time could elucidate a cause-and-effect relationship between insufficient sleep and obesity.
睡眠不足和肥胖在美国很常见。睡眠受限会导致重要的神经认知变化,包括白天过度嗜睡和情绪改变。这可能会导致与工作相关的伤害和汽车事故。有证据表明睡眠不足与可能导致肥胖的激素变化有关。本文研究了异质性成年初级保健人群中睡眠受限与肥胖之间的关联。
来自4家初级保健机构的1001名患者参与了这项前瞻性研究。患者完成了一份由护士或研究协调员管理的问卷,内容涉及人口统计学、医疗问题、睡眠习惯和睡眠障碍。专业人员在办公室测量身高和体重。根据体重指数(BMI,计算方法为体重(千克)除以身高(米)的平方)将患者分为正常体重(<25)、超重(25 - 29.9)、肥胖(30 - 39.9)或极度肥胖(≥40),然后分析体重指数与报告的每24小时总睡眠时间之间的关系。
924名年龄在18至91岁之间的患者的可分析表格显示:(1)平均BMI为30;(2)女性睡眠时间比男性长;(3)超重和肥胖患者的睡眠时间比BMI正常的患者少(从正常组到肥胖组,患者报告的睡眠时间呈近似线性减少);(4)在极度肥胖患者中,睡眠时间减少的这种趋势被逆转。
本研究发现睡眠时间减少与超重和肥胖状态有关。控制总睡眠时间的干预措施可能会阐明睡眠不足与肥胖之间的因果关系。