van Hooren Susan A H, Valentijn Susanne A M, Bosma Hans, Ponds Rudolf W H M, van Boxtel Martin P J, Jolles Jelle
European Graduate School of Neuroscience (Euron), Maastricht University, the Netherlands.
J Gerontol B Psychol Sci Soc Sci. 2005 Jan;60(1):P57-60. doi: 10.1093/geronb/60.1.p57.
The aim of this study was to determine whether physical and psychological functioning can predict 6-year cognitive decline in older adults. A group of 669 participants aged 60 to 81 years was recruited from a longitudinal study (the Maastricht Aging Study). Physical functioning was measured in terms of perceived health and instrumental activities of daily living. Psychological functioning or mood was evaluated by the Depression and Anxiety subscales of the Symptom Check List-90. Although physical functioning and psychological functioning were related to several measures of cognitive functioning at baseline, psychological functioning was specifically related to memory functioning 6 years later. Poor psychological functioning (i.e., depressive and anxiety symptomatology), rather than poor physical health, may have the strongest implications for long-term cognitive functioning in older men and women.
本研究的目的是确定身体和心理功能是否能够预测老年人6年的认知衰退情况。从一项纵向研究(马斯特里赫特衰老研究)中招募了一组669名年龄在60至81岁之间的参与者。身体功能通过自我感知健康状况和日常生活工具性活动来衡量。心理功能或情绪通过症状自评量表90的抑郁和焦虑分量表进行评估。尽管身体功能和心理功能在基线时与多种认知功能指标相关,但心理功能与6年后的记忆功能具体相关。心理功能不佳(即抑郁和焦虑症状)而非身体健康不佳,可能对老年男性和女性的长期认知功能有最强的影响。