Watanabe Nobuo, Masuda Takaya, Iida Tomoya, Kataoka Hiroyuki, Fujimoto Tetsuo, Takatani Setsuo
Department of Artificial Organs, Institute of Biomaterial and Bioengineering, Tokyo Medical and Dental University, Chiyoda-ku, Tokyo, Japan.
Artif Organs. 2005 Jan;29(1):26-35. doi: 10.1111/j.1525-1594.2004.29012.x.
Secondary flow in the centrifugal blood pump helps to enhance the washout effect and to minimize thrombus formation. On the other hand, it has an adverse effect on pump efficiency. Excessive secondary flow may induce hemolytic effects. Understanding the secondary flow is thus important to the design of a compact, efficient, biocompatible blood pump. This study examined the secondary flow in a radial coupled centrifugal blood pump based on a simple particle tracking velocimetry (PTV) technique. A radial magnetically coupled centrifugal blood pump has a bell-shaped narrow clearance between the impeller inner radius and the pump casing. In order to vary the flow levels through the clearance area, clearance widths of 0.25 mm and 0.50 mm and impeller washout holes with diameters of 0 mm, 2.5 mm, and 4 mm were prepared. A high-speed video camera (2000 frames per second) was used to capture the particle images from which radial flow components were derived. The flow in the space behind the impeller was assumed to be laminar and Couette type. The larger the inner clearance or diameter of washout hole, the greater was the secondary flow rate. Without washout holes, the flow behind the impeller resulted in convection. The radial flow through the washout holes of the impeller was conserved in the radial as well as in the axial direction behind the impeller. The increase in the secondary flow reduced the net pump efficiency. Simple PTV was successful in quantifying the flow in the space behind the impeller. The results verified the hypothesis that the flow behind the impeller was theoretically Couette along the circumferential direction. The convection flow observed behind the impeller agreed with the reports of other researchers. Simple PTV was effective in understanding the fluid dynamics to help improve the compact, efficient, and biocompatible centrifugal blood pump for safe clinical applications.
离心式血泵中的二次流有助于增强冲洗效果并使血栓形成最小化。另一方面,它对泵的效率有不利影响。过多的二次流可能会引发溶血效应。因此,了解二次流对于设计紧凑、高效且生物相容的血泵很重要。本研究基于一种简单的粒子跟踪测速(PTV)技术,对径向耦合离心式血泵中的二次流进行了研究。径向磁耦合离心式血泵在叶轮内半径与泵壳之间有一个钟形窄间隙。为了改变通过间隙区域的流量水平,准备了0.25毫米和0.50毫米的间隙宽度以及直径为0毫米、2.5毫米和4毫米的叶轮冲洗孔。使用高速摄像机(每秒2000帧)来捕捉粒子图像,从中得出径向流分量。叶轮后方空间内的流动被假定为层流和库埃特流型。内部间隙或冲洗孔直径越大,二次流率就越大。没有冲洗孔时,叶轮后方的流动会导致对流。通过叶轮冲洗孔的径向流在叶轮后方的径向以及轴向上都得以保留。二次流的增加降低了泵的净效率。简单的PTV成功地量化了叶轮后方空间内的流动。结果验证了叶轮后方的流动在理论上沿圆周方向为库埃特流的假设。在叶轮后方观察到的对流与其他研究人员的报告一致。简单的PTV在理解流体动力学方面很有效,有助于改进紧凑、高效且生物相容的离心式血泵,以用于安全的临床应用。