扁平苔藓与丙型肝炎病毒感染：一项流行病学研究。

Lichen planus and hepatitis C virus infection: an epidemiologic study.

作者信息

Harman M, Akdeniz S, Dursun M, Akpolat N, Atmaca S

机构信息

Department of Dermatology and Venerology, Faculty of Medicine, University of Dicle, Diyarbakir, Turkey.

出版信息

Int J Clin Pract. 2004 Dec;58(12):1118-9. doi: 10.1111/j.1742-1241.2004.00214.x.

DOI:10.1111/j.1742-1241.2004.00214.x

PMID:15646408

Abstract

The reported prevalence of hepatitis C virus (HCV) infection in patients with lichen planus (LP) shows variations from different regions. The aim of this study was to investigate the prevalence of HCV infection in patients with LP, in Diyarbakir region of Turkey. A total of 128 patients with LP and 128 healthy controls were detected for HCV infection, using a third generation enzyme-linked immunosorbent assay. Eight of 128 patients (6.25%) with LP were found to have anti-HCV antibodies, whereas only one patient (0.78%) in control group was found to have anti-HCV antibodies. A statistically significant difference was found between LP and control group (p < 0.001). In conclusion, the coexistence of HCV infection and lichen planus is more than coincidental, and it is appropriate to screen all patients with lichen planus for HCV infection.

摘要

据报道，扁平苔藓（LP）患者中丙型肝炎病毒（HCV）感染的患病率在不同地区存在差异。本研究的目的是调查土耳其迪亚巴克尔地区LP患者中HCV感染的患病率。使用第三代酶联免疫吸附试验对128例LP患者和128例健康对照进行HCV感染检测。128例LP患者中有8例（6.25%）抗HCV抗体呈阳性，而对照组中只有1例患者（0.78%）抗HCV抗体呈阳性。LP组和对照组之间存在统计学显著差异（p < 0.001）。总之，HCV感染与扁平苔藓并存并非偶然，对所有扁平苔藓患者进行HCV感染筛查是合适的。