Sharkey Joseph R, Browne Barry, Ory Marcia G, Wang Suojin
Department of Social and Behavioral Health, School of Rural Public Health, Texas A&M University System Health Sciences Center, College Station, TX 77840, USA.
Pharmacoepidemiol Drug Saf. 2005 Oct;14(10):715-23. doi: 10.1002/pds.1066.
The measurement of prescription medication use is usually through a simple count of medications, which tends to ignore therapeutic categories. This research investigated prescription medication use among homebound older adults, by documenting the therapeutic prescription medication categories used by these individuals and identifying the factors associated with use of multiple therapeutic categories.
Baseline Nutrition and Function Study (2000-2001) data from 326 homebound older persons who completed the medication review component (visual inspection of medications) of the baseline in-home interview and used > or =1 prescribed medication were included in this analysis.
More than 40% (n = 133) regularly took medications from three to four different therapeutic categories and 31.6% (n = 103) used > or =5 different therapeutic categories. The use of respiratory medications declined with increasing age, and more women than men used diuretic and thyroid replacement medications. Independent of other factors, increased use of multiple therapeutic categories was associated with sociodemographic characteristics (gender, age, living arrangement, marital status and medication coverage), medical conditions (diabetes, heart problems and lung disease) and inability to self-manage medications.
Our findings suggest that individual characteristics and medical conditions may help identify homebound elders at high risk for using prescription medications from an increased number of different therapeutic categories. This observation may help clinicians and community-based providers of services to older persons to be aware of differences in therapeutic medication use within an older population, and how patterns of use may alter service needs.
处方药使用情况的衡量通常是通过简单统计药物数量,这往往会忽略治疗类别。本研究通过记录居家老年人使用的治疗性处方药类别,并确定与使用多种治疗类别相关的因素,来调查居家老年人的处方药使用情况。
本分析纳入了来自基线营养与功能研究(2000 - 2001年)的数据,这些数据来自326名居家老年人,他们完成了基线居家访谈中的药物审查部分(对药物进行目视检查)且使用了≥1种处方药。
超过40%(n = 133)的人定期服用三到四种不同治疗类别的药物,31.6%(n = 103)的人使用≥5种不同治疗类别的药物。呼吸系统药物的使用随年龄增长而减少,使用利尿剂和甲状腺替代药物的女性多于男性。独立于其他因素,多种治疗类别的药物使用增加与社会人口统计学特征(性别、年龄、居住安排、婚姻状况和药物保险范围)、医疗状况(糖尿病、心脏问题和肺部疾病)以及无法自我管理药物有关。
我们的研究结果表明,个体特征和医疗状况可能有助于识别居家老年人中使用不同治疗类别药物数量增加的高风险人群。这一观察结果可能有助于临床医生和为老年人提供社区服务的人员了解老年人群体中治疗性药物使用的差异,以及使用模式如何改变服务需求。