Kuniyoshi Yukio, Koja Kageharu, Miyagi Kazufumi, Uezu Tooru, Yamashiro Satoshi, Arakaki Katuya, Nagano Takaaki, Mabuni Katuhito, Senaha Shigenobu
Thoracic and Cardiovascular Surgery Division, Department of Bioregulatory Medicine, School of Medicine, University of the Ryukyus, Okinawa, Japan.
Ann Thorac Cardiovasc Surg. 2004 Dec;10(6):367-72.
To evaluate the effectiveness of selective visceral perfusion during repair of an thoracoabdominal aortic aneurysm (TAAA), we compared the postoperative renal and hepatic functions (blood urea nitrogen, serum creatinine, total bilirubin, glutamate pyruvate transaminase) between the two groups with and without perfusion.
We operated on 52 patients with TAAA. Among them, the visceral vessels were reconstructed in 22 patients with selective visceral perfusion and in 12 patients without perfusion. The average selective perfusion time was 49.5+/-25.5 min. in the celiac and superior mesenteric arteries and 32.8+/-18.8 min. in the renal arteries. The average perfusion flow rate per each visceral vessel was 155.4+/-97.4 ml/min.
There were five hospital deaths. There was no significant difference between the groups in the postoperative value of four factors. The selective perfusion time for vessel reconstruction in the selective visceral perfusion group was significantly longer than the arterial clamp time for vessel reconstruction in the non-perfusion group (49.5+/-25.5 min. vs. 25.6+/-13.4 min.).
Our selective visceral perfusion method is not only beneficial for organ protection, but also provides us with the necessary time to reimplant the visceral as well as intercostal or lumbar arteries.
为评估胸腹主动脉瘤(TAAA)修复术中选择性内脏灌注的有效性,我们比较了有灌注组和无灌注组术后的肾功能和肝功能(血尿素氮、血清肌酐、总胆红素、谷丙转氨酶)。
我们对52例TAAA患者进行了手术。其中,22例患者在选择性内脏灌注下重建内脏血管,12例患者未进行灌注。腹腔干和肠系膜上动脉的平均选择性灌注时间为49.5±25.5分钟,肾动脉的平均选择性灌注时间为32.8±18.8分钟。每个内脏血管的平均灌注流速为155.4±97.4毫升/分钟。
有5例患者在住院期间死亡。两组患者术后四项指标的值无显著差异。选择性内脏灌注组血管重建的选择性灌注时间明显长于非灌注组血管重建的动脉阻断时间(49.5±25.5分钟对25.6±13.4分钟)。
我们的选择性内脏灌注方法不仅有利于器官保护,还为我们重新植入内脏以及肋间或腰动脉提供了必要的时间。