Vosshall Leslie B, Stensmyr Marcus C
Laboratory of Neurogenetics and Behavior, The Rockefeller University, Box 63, New York, NY 10021, USA.
Neuron. 2005 Jan 20;45(2):179-81. doi: 10.1016/j.neuron.2005.01.001.
Odorant binding proteins (OBPs) are abundant proteins of unknown function expressed at high levels in insect and vertebrate chemosensory organs. In this issue of Neuron, Xu et al. show that Drosophila OBP76a is necessary for fruit flies to respond to the aggregation pheromone 11-cis vaccenyl acetate. The results suggest a mechanism by which this OBP is intimately involved in pheromone signal transduction.
气味结合蛋白(OBPs)是在昆虫和脊椎动物化学感受器官中高水平表达的功能未知的丰富蛋白质。在本期《神经元》杂志中,徐等人表明,果蝇OBP76a对于果蝇对聚集信息素11-顺式醋酸vaccenyl的反应是必需的。结果提示了一种该OBP密切参与信息素信号转导的机制。