丙二醇在用于儿科1H - MRS的LCModel基础集中是必不可少的。

Propylene glycol is essential in the LCModel basis set for pediatric 1H-MRS.

作者信息

Oakden Wendy K, Noseworthy Michael D

机构信息

The Imaging Research Centre, Brain Body Institute, St. Joseph's Healthcare, Hamilton, Ontario, Canada.

出版信息

J Comput Assist Tomogr. 2005 Jan-Feb;29(1):136-9. doi: 10.1097/01.rct.0000145860.13963.2f.

DOI:10.1097/01.rct.0000145860.13963.2f

PMID:15665701

Abstract

Propylene glycol (PG) is an organic solvent used in a variety of parenterally injected pharmaceutical preparations. In this current study, we analyzed neonatal brains following routine MRS evaluation at 1.5 T, using the LCModel software, with and without the addition of PG to the analysis basis-set. We suggest including PG in the LCModel basis-set for neonatal brain H-MRS to improve the discrimination and quantification of lactate and inositol.

摘要

丙二醇（PG）是一种有机溶剂，用于多种肠胃外注射用药物制剂。在本研究中，我们在1.5T场强下，使用LCModel软件，对新生儿脑部进行常规磁共振波谱（MRS）评估，分析了在分析基集中添加和不添加PG的情况。我们建议在新生儿脑部氢磁共振波谱（H-MRS）的LCModel基集中纳入PG，以改善乳酸和肌醇的鉴别与定量分析。