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大脑半球切除术:手术技术描述

Hemispherotomy: description of surgical technique.

作者信息

Smith Joseph R, Fountas Kostas N, Lee Mark R

机构信息

Department of Neurosurgery, Medical College of Georgia, Augusta, GA, USA.

出版信息

Childs Nerv Syst. 2005 Jun;21(6):466-72. doi: 10.1007/s00381-004-1067-3. Epub 2005 Jan 22.

Abstract

INTRODUCTION

Hemispherectomy constitutes an established surgical method in the management of patients with medically intractable epilepsy, secondary to severe unilateral hemisphere damage. The well-established association of the anatomical hemispherectomy initially described with severe complications such as late hydrocephalus has led to the development of less resective and more disconnecting procedures. All these technical variations of hemispherotomy carry less favorable outcomes compared with anatomic hemispherectomy, but significantly fewer complications.

METHODS

In our current communication, we outline the indications and the surgical technique of hemispherotomy and report our experience of the clinical application of this surgical procedure.

RESULTS

In our clinical series, the 5-year follow-up shows that 66.6% of our patients (6 out of 9) had class I outcome according to Engel's classification system, 22.2% (2 out of 9) class II outcome, while 11.1% (1 out of 9) had class III outcome. No mortality occurred in the current series and operative blood loss was significantly lowered.

CONCLUSION

Hemispherotomy represents a less efficacious technique compared with anatomic hemispherectomy, but is a safe and technically simple surgical alternative for the management of patients with medically intractable seizures.

摘要

引言

半球切除术是治疗因严重单侧半球损伤导致药物难治性癫痫患者的一种既定手术方法。最初描述的解剖性半球切除术与诸如晚期脑积水等严重并发症之间的既定关联,促使了切除范围较小且切断联系更多的手术方法的发展。与解剖性半球切除术相比,所有这些半球切开术的技术变体疗效较差,但并发症明显更少。

方法

在我们当前的交流中,我们概述了半球切开术的适应症和手术技术,并报告了我们在该手术临床应用方面的经验。

结果

在我们的临床系列中,5年随访显示,根据恩格尔分类系统,我们66.6%的患者(9例中的6例)达到I级预后,22.2%(9例中的2例)达到II级预后,而11.1%(9例中的1例)达到III级预后。在当前系列中未发生死亡,手术失血量显著降低。

结论

与解剖性半球切除术相比,半球切开术是一种疗效较差的技术,但对于治疗药物难治性癫痫患者而言,是一种安全且技术上简单的手术选择。

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