Ehrlich J R, Hohnloser S H
Abteilung für klinische Elektrophysiologie, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.
Z Kardiol. 2005 Jan;94(1):14-22. doi: 10.1007/s00392-005-0166-9.
Atrial fibrillation is a very common rhythm disorder that can be therapeutically reverted into sinus rhythm by means of pharmacological or electrical cardioversion. This article reviews options for drug therapy and tries to elucidate the mechanisms of AF termination by antiarrhythmics. We will explain the clinical basis of different therapeutic approaches and review the efficacy of selected substances according to recent clinical studies. Finally, we will focus on some important aspects of anticoagulation in the setting of pharmacological cardioversion.
心房颤动是一种非常常见的节律紊乱,可通过药物或电复律在治疗上恢复为窦性心律。本文综述了药物治疗的选择,并试图阐明抗心律失常药物终止房颤的机制。我们将解释不同治疗方法的临床依据,并根据近期临床研究回顾所选药物的疗效。最后,我们将重点关注药物复律情况下抗凝的一些重要方面。